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M Eileen Dolan Selected Research

NU2058

5/2009The kinase inhibitor O6-cyclohexylmethylguanine (NU2058) potentiates the cytotoxicity of cisplatin by mechanisms that are independent of its effect upon CDK2.

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M Eileen Dolan Research Topics

Disease

52Neoplasms (Cancer)
01/2022 - 05/2002
10Peripheral Nervous System Diseases (PNS Diseases)
01/2022 - 08/2012
9Testicular Neoplasms (Testicular Cancer)
01/2022 - 03/2009
8Tinnitus
05/2022 - 03/2014
8Ototoxicity
05/2022 - 09/2007
8Glioma (Gliomas)
05/2014 - 05/2002
7Hearing Loss (Hearing Impairment)
05/2022 - 10/2016
7Leukemia
02/2015 - 03/2002
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
09/2013 - 11/2007
5Breast Neoplasms (Breast Cancer)
06/2020 - 11/2004
5Head and Neck Neoplasms (Head and Neck Cancer)
05/2011 - 01/2005
4Hypertension (High Blood Pressure)
05/2022 - 10/2016
4Lung Neoplasms (Lung Cancer)
01/2021 - 07/2003
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 11/2008
4Drug-Related Side Effects and Adverse Reactions
05/2014 - 04/2005
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
02/2015 - 11/2007
3Hematologic Neoplasms (Hematological Malignancy)
10/2013 - 06/2007
3Brain Neoplasms (Brain Tumor)
02/2007 - 11/2003
2Hand-Foot Syndrome
06/2020 - 05/2014
2Nausea
01/2019 - 04/2012
2Gram-Negative Bacterial Infections
03/2017 - 10/2013
2Colorectal Neoplasms (Colorectal Cancer)
05/2014 - 10/2005
2Neutropenia
04/2012 - 06/2009
2Ovarian Neoplasms (Ovarian Cancer)
08/2011 - 11/2008
2Disease Susceptibility (Diathesis)
10/2010 - 09/2009
2Microsatellite Instability
11/2007 - 10/2005
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2022
1Vertigo (Positional Vertigo)
11/2021
1Dizziness (Lightheadedness)
11/2021
1Diarrhea
06/2020
1Raynaud Disease (Raynaud's Disease)
10/2019
1Hypogonadism (Hypergonadotropic Hypogonadism)
01/2019
1Vomiting
01/2019
1Fibrosis (Cirrhosis)
05/2018
1Genetic Predisposition to Disease (Genetic Predisposition)
05/2018
1Inflammation (Inflammations)
05/2018
1Mesothelioma
01/2018
1Adenocarcinoma of Lung
01/2018
1Hypercholesterolemia
10/2017
1Deafness (Deaf Mutism)
01/2017
1Male Germ Cell Tumor
10/2016
1Prostatic Neoplasms (Prostate Cancer)
10/2016
1Mental Disorders (Mental Disorder)
11/2014
1Obesity
10/2014
1Glioblastoma (Glioblastoma Multiforme)
05/2014
1Bilateral Hearing Loss
03/2014

Drug/Important Bio-Agent (IBA)

20Cisplatin (Platino)FDA LinkGeneric
05/2022 - 07/2003
11Pharmaceutical PreparationsIBA
01/2021 - 07/2003
10DNA (Deoxyribonucleic Acid)IBA
02/2015 - 03/2002
10O(6)-benzylguanineIBA
11/2008 - 05/2002
9Temozolomide (Temodar)FDA LinkGeneric
05/2014 - 09/2002
8PlatinumIBA
12/2020 - 04/2005
7Proteins (Proteins, Gene)FDA Link
01/2022 - 08/2002
6MethyltransferasesIBA
09/2011 - 12/2003
5Carboplatin (JM8)FDA LinkGeneric
03/2014 - 01/2006
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2009 - 03/2002
5Carmustine (FIVB)FDA Link
02/2007 - 05/2002
4Etoposide (VP 16)FDA LinkGeneric
01/2021 - 06/2007
4MicroRNAs (MicroRNA)IBA
01/2018 - 09/2009
4Daunorubicin (Cerubidine)FDA LinkGeneric
10/2014 - 06/2007
4Cytarabine (Cytosar-U)FDA LinkGeneric
05/2013 - 06/2008
4Alkyl and Aryl TransferasesIBA
02/2007 - 09/2002
3Capecitabine (Xeloda)FDA Link
06/2020 - 08/2012
3Anti-Bacterial Agents (Antibiotics)IBA
03/2017 - 06/2007
3Paclitaxel (Taxol)FDA LinkGeneric
10/2015 - 08/2011
3Irinotecan (Camptosar)FDA LinkGeneric
06/2009 - 08/2002
3O-(6)-methylguanineIBA
09/2008 - 09/2002
3Alkylating AgentsIBA
07/2007 - 06/2006
2Biological ProductsIBA
01/2018 - 09/2008
2Pemetrexed (MTA)FDA Link
01/2018 - 04/2012
2Colistin (Coly-Mycin)FDA Link
03/2017 - 10/2013
2CytosineIBA
11/2014 - 05/2014
2Messenger RNA (mRNA)IBA
09/2013 - 10/2011
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
09/2013 - 06/2008
2IfosfamideFDA LinkGeneric
08/2007 - 03/2002
2EnzymesIBA
11/2004 - 12/2003
1Antidepressive Agents (Antidepressants)IBA
11/2021
1Testosterone (Sustanon)FDA Link
01/2019
1Sex Hormone-Binding GlobulinIBA
01/2019
1human ERBB2 proteinIBA
02/2018
1Estrogen ReceptorsIBA
02/2018
1P-2 (P 2)IBA
10/2017
1Glycoproteins (Glycoprotein)IBA
01/2017
1Neuroprotective AgentsIBA
01/2017
1Prednisone (Sone)FDA LinkGeneric
10/2016
1Bevacizumab (Avastin)FDA Link
10/2016
1Docetaxel (Taxotere)FDA Link
10/2016
1taxaneIBA
01/2016
1Vincristine (Oncovin)FDA LinkGeneric
02/2015
1DecitabineFDA Link
05/2014
1NitrogenIBA
10/2013

Therapy/Procedure

27Drug Therapy (Chemotherapy)
05/2022 - 12/2003
19Therapeutics
01/2019 - 03/2002
2Drug Tapering
01/2019 - 01/2017
2Adjuvant Chemotherapy
02/2018 - 11/2006
1Hearing Aids (Hearing Aid)
05/2022
1Radiotherapy
11/2021
1Complementary Therapies (Alternative Medicine)
01/2019
1Ambulatory Care (Outpatient Care)
02/2015
1Stem Cell Transplantation
10/2013